What does code 81405 cost?

Across the published hospital price files, the disclosed cash price for 81405 ranges from $50.76 to $3,092. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Will this be my final bill?

Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.

81405 is the billing code hospitals use to identify "HC SMITH-LEMI-OPTIZ SCREEN" on their published price files. We use it to line up the same service across different hospitals.

Why do prices for this code differ between hospitals?

Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.

What this page is not

It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

81405

HCPCS

HC SMITH-LEMI-OPTIZ SCREEN

Verified from hospital fileNot a bill estimate

iDirect answer

Based on the latest published hospital price files, code 81405 (HC SMITH-LEMI-OPTIZ SCREEN) appears at 33 hospitals with disclosed cash prices from $50.76 to $3,092. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Published-price availability

hospitals publish a price

list this service without a published price

101

Cash

101

List

Negotiated

Allowed

A blank price (“—”) means a hospital names this service but did not publish a dollar amount — it is not a free service or a $0 price.

Compare 81405 prices

Filter by hospital, city, setting, or payer — the summary and charts update with your filters.

Based on hospital-published prices verified from each hospital’s own file. Coverage expands as data is verified.

Published cash prices for code 81405 vary by about 61× across the 30 hospitals with disclosed prices here — from $50.76 to $3,092. Shopping around can matter.

Hospitals

137

Prices shown

$50.76

Lowest cash

$3,092

Highest cash

code 81405 cash price101 disclosed · 30 hospitals

$50.76median ~$436$3,092

Lowest cash price by hospital

Cash price by city

Reflects your current filters.

Cash price by city$50.76 – $1,770

Morganfield · 1 hospital$50.76
Princeton · 1 hospital$57.24
Stanford · 1 hospital$66.55–$288
Burlington · 1 hospital$170–$1,770
Fond Du Lac · 1 hospital$170–$1,770
Grafton · 1 hospital$170–$685

137 prices shown.

Service	Hospital	Code	List price	Cash price	Negotiated range	Allowed (median)
HC SMITH-LEMI-OPTIZ SCREEN Inpatient & outpatient	Endeavor Health Edward Hospital	81405 HCPCS	$3,092	$3,092	—	—
HC ALPHA GLOBIN GENE ANALYSIS Inpatient & outpatient	Endeavor Health Edward Hospital	81405 HCPCS	$3,092	$3,092	—	—
HC MEN 2 MUTATION SCREEN Inpatient & outpatient	Endeavor Health Edward Hospital	81405 HCPCS	$2,292	$2,292	—	—
HC MOLEC PATH PROCED LEVEL 6 Inpatient & outpatient	Endeavor Health Edward Hospital	81405 HCPCS	$3,092	$3,092	—	—
Mopath procedure level 6 Outpatient	Endeavor Health Edward Hospital	81405 HCPCS	—	—	$301 – $510	—
21 HYDROXYLASE GENE ANALYSIS Inpatient	Advocate Christ Medical Center	81405 CPT	$2,390	$1,195	$1,044 – $1,912	—
Hc Lrsv- Molecular Pathology Procedure Level 6 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Mol Path Proc Lvl6 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Tp53 >5 Targeted Sequence Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Ret Targeted Sequences Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Hyperparathyroidism Panel, Cefr Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Hyperparathyroidism Panel, Mem1 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Msk Adult Mds/Aml Panel Tp53 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Hereditary Hemorrhagic Telangectasia Panel - Eng Del Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Hereditary Hemorrhagic Telangectasia Panel - Smad4 Del/Dup Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Msk Acute Lymphoblastic Leukemia Panel Tp53 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Diamond-Blackfan Anemia Panel Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Holoprosencephaly Panel Fgfr1 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Slc2A1 Mutation Analysis Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Nsd1 Mutation Analysis Nsd1 Del/Dupl Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Tcf4 Mutation Analysis Tcf4 Del/Dupl Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Tier 2: Slc16A2 (Mct8) Mutation Analysis? Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc 46,Xx Disorders Cyp11B1 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc 46,Xx Disorders Wt1 Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—
Hc Hypercholesterolemia Panel Ldlr Del/Dupl Inpatient & outpatient	University of Chicago Medical Center	81405 HCPCS	—	—	—	—

How to read these prices

Cash price: The discounted self-pay price for paying directly, without insurance.
List price: The hospital’s full undiscounted charge — rarely what anyone pays.
Negotiated rate: A rate for a specific insurer and plan; your share depends on your benefits.
Allowed amount: A historical reference for what was actually allowed, where disclosed.

Hospitals that publish 81405 prices

Open a hospital to see this code in the context of its full published prices.

Endeavor Health Edward Hospital Advocate Christ Medical Center University of Chicago Medical Center Advocate Illinois Masonic Medical Center Advocate Lutheran General Hospital Advocate Condell Medical Center Advocate Good Samaritan Hospital Advocate South Suburban Hospital Froedtert Menomonee Falls Hospital Aurora BayCare Medical Center Aurora Medical Center Burlington Munson Healthcare Charlevoix Hospital Munson Healthcare Manistee Hospital Aurora Medical Center Bay Area Aurora Medical Center Fond du Lac Aurora Medical Center Grafton Aurora Medical Center Kenosha Aurora Lakeland Medical Center Froedtert West Bend Hospital Froedtert Holy Family Memorial Hospital Froedtert Community Hospital - Mequon Froedtert Community Hospital - New Berlin Froedtert Community Hospital - Oak Creek Kalkaska Memorial Health Center Munson Healthcare Cadillac Munson Medical Center Deaconess Gibson Hospital Deaconess Union County Hospital The Women's Hospital Deaconess Illinois Medical Center Beacon Dowagiac Stanford Health Care Texas Health Center for Diagnostics and Surgery Plano

Code 81405: frequently asked

What does code 81405 cost?: Across the published hospital price files, the disclosed cash price for 81405 ranges from $50.76 to $3,092. This is public hospital price transparency data, not a guaranteed estimate of your bill.
Will this be my final bill?: Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.
What is code 81405?: 81405 is the billing code hospitals use to identify "HC SMITH-LEMI-OPTIZ SCREEN" on their published price files. We use it to line up the same service across different hospitals.
Why do prices for this code differ between hospitals?: Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.
What this page is not: It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

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