What does code 81257 cost?

Across the published hospital price files, the disclosed cash price for 81257 ranges from $100 to $1,760. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Will this be my final bill?

Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.

81257 is the billing code hospitals use to identify "HC ALPHA THALASSEMIA" on their published price files. We use it to line up the same service across different hospitals.

Why do prices for this code differ between hospitals?

Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.

What this page is not

It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

81257

HCPCS

HC ALPHA THALASSEMIA

Verified from hospital fileNot a bill estimate

iDirect answer

Based on the latest published hospital price files, code 81257 (HC ALPHA THALASSEMIA) appears at 34 hospitals with disclosed cash prices from $100 to $1,760. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Published-price availability

hospitals publish a price

list this service without a published price

Cash

List

Negotiated

Allowed

A blank price (“—”) means a hospital names this service but did not publish a dollar amount — it is not a free service or a $0 price.

Compare 81257 prices

Filter by hospital, city, setting, or payer — the summary and charts update with your filters.

Based on hospital-published prices verified from each hospital’s own file. Coverage expands as data is verified.

Published cash prices for code 81257 vary by about 18× across the 28 hospitals with disclosed prices here — from $100 to $1,760. Shopping around can matter.

Hospitals

Prices shown

$100

Lowest cash

$1,760

Highest cash

code 81257 cash price30 disclosed · 28 hospitals

$100median ~$338$1,760

Lowest cash price by hospital

Cash price by city

Reflects your current filters.

Cash price by city$100 – $235

Marion · 1 hospital$100
Mission Viejo · 1 hospital$221
Orange · 1 hospital$221
Fullerton · 1 hospital$221
Apple Valley · 1 hospital$221
Petaluma · 1 hospital$235

38 prices shown.

Service	Hospital	Code	List price	Cash price	Negotiated range	Allowed (median)
HC ALPHA THALASSEMIA Inpatient & outpatient	Endeavor Health Edward Hospital	81257 HCPCS	$1,076	$1,076	—	—
Hba1/hba2 gene Outpatient	Endeavor Health Edward Hospital	81257 HCPCS	—	—	$102 – $173	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Advocate Christ Medical Center	81257 CPT	$985	$493	$430 – $788	—
Hc Hba1/Hba1 Alpha Globin 1 And Alpha Globin 2 Gene Analysis, For Common Deletions Or Variant Inpatient & outpatient	University of Chicago Medical Center	81257 HCPCS	—	—	—	—
Hba1/hba2 gene Outpatient	University of Chicago Medical Center	81257 HCPCS	—	—	—	—
ALPHA THALASSEMIA GENE ANALYSIS Outpatient	Advocate Illinois Masonic Medical Center	81257 CPT	$985	$493	$102 – $831	—
HB R HBA1/HB2 (ALPHA GLOBLIN) GEN ANLYS Inpatient & outpatient	Endeavor Health Swedish Hospital	81257 HCPCS	$716	$716	—	—
HB R HB R HBA1/HB2 (ALPHA GLOBLIN) GEN ANLYS Inpatient & outpatient	Endeavor Health Swedish Hospital	81257 HCPCS	$274	$274	—	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Advocate Lutheran General Hospital	81257 CPT	$985	$493	$430 – $788	—
ALPHA THALASSEMIA GENE ANALYSIS Outpatient	Advocate Condell Medical Center	81257 CPT	$985	$493	$102 – $827	—
ALPHA THALASSEMIA GENE ANALYSIS Outpatient	Advocate Good Samaritan Hospital	81257 CPT	$985	$493	$102 – $817	—
ALPHA THALASSEMIA GENE ANALYSIS Outpatient	Advocate South Suburban Hospital	81257 CPT	$985	$493	$102 – $959	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Aurora BayCare Medical Center	81257 CPT	$675	$338	$405 – $574	—
HBA1/HBA2 GENE Outpatient	Aurora Medical Center Burlington	81257 CPT	—	—	$81.81 – $359	—
HBA1/HBA2 GENE Outpatient	Aurora Medical Center Bay Area	81257 CPT	—	—	$81.81 – $359	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Aurora Medical Center Fond du Lac	81257 CPT	$675	$338	$405 – $574	—
ALPHA THALASSEMIA GENE ANALYSIS Outpatient	Aurora Medical Center Fond du Lac	81257 CPT	$675	$338	$81.81 – $574	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Aurora Medical Center Grafton	81257 CPT	$675	$338	$405 – $574	—
ALPHA THALASSEMIA GENE ANALYSIS Inpatient	Aurora Medical Center Kenosha	81257 CPT	$675	$338	$405 – $574	—
HBA1/HBA2 GENE Outpatient	The Women's Hospital	81257 CPT	—	—	$40.90 – $251	—
HC ALPHA THALASSEMIA DNA REF Inpatient	Deaconess Illinois Medical Center	81257 CPT	$527	$100	$100 – $474	—
HBA1/HBA2 GENE Outpatient	Beacon Dowagiac	81257 CPT	—	—	$85.90 – $102	—
HC HBA1/HBA2 GENE ANALYSIS COMMON DELETIONS/VARIANT LAB Inpatient & outpatient	Providence Alaska Medical Center	81257 HCPCS	$2,257	$1,760	—	—
HC HBA1/HBA2 GENE ANALYSIS COMMON DELETIONS/VARIANT LAB Inpatient & outpatient	Providence Kodiak Island Medical Center	81257 HCPCS	$459	$358	—	—
HC Athal Alpha Thalassemia Inpatient & outpatient	Stanford Health Care	81257 HCPCS	$1,261	$504	—	—

How to read these prices

Cash price: The discounted self-pay price for paying directly, without insurance.
List price: The hospital’s full undiscounted charge — rarely what anyone pays.
Negotiated rate: A rate for a specific insurer and plan; your share depends on your benefits.
Allowed amount: A historical reference for what was actually allowed, where disclosed.

Hospitals that publish 81257 prices

Open a hospital to see this code in the context of its full published prices.

Endeavor Health Edward Hospital Advocate Christ Medical Center University of Chicago Medical Center Advocate Illinois Masonic Medical Center Endeavor Health Swedish Hospital Advocate Lutheran General Hospital Advocate Condell Medical Center Advocate Good Samaritan Hospital Advocate South Suburban Hospital Aurora BayCare Medical Center Aurora Medical Center Burlington Aurora Medical Center Bay Area Aurora Medical Center Fond du Lac Aurora Medical Center Grafton Aurora Medical Center Kenosha The Women's Hospital Deaconess Illinois Medical Center Beacon Dowagiac Providence Alaska Medical Center Providence Kodiak Island Medical Center Stanford Health Care Stanford Health Care Tri-Valley Providence Seward Hospital Providence Valdez Medical Center Petaluma Valley Hospital Queen of The Valley Medical Center Redwood Memorial Hospital Providence St Joseph Hospital Eureka Santa Rosa Memorial Hospital Texas Health Center for Diagnostics and Surgery Plano Providence Mission Hospital - Mission Viejo Providence St Joseph Hospital Orange St Jude Medical Center St Mary Medical Center

Code 81257: frequently asked

What does code 81257 cost?: Across the published hospital price files, the disclosed cash price for 81257 ranges from $100 to $1,760. This is public hospital price transparency data, not a guaranteed estimate of your bill.
Will this be my final bill?: Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.
What is code 81257?: 81257 is the billing code hospitals use to identify "HC ALPHA THALASSEMIA" on their published price files. We use it to line up the same service across different hospitals.
Why do prices for this code differ between hospitals?: Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.
What this page is not: It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

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Hospitals publishing code 81257 by state

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