What does code 81223 cost?

Across the published hospital price files, the disclosed cash price for 81223 ranges from $239 to $5,121. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Will this be my final bill?

Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.

81223 is the billing code hospitals use to identify "HC CF (CFTR) SEQUENCING" on their published price files. We use it to line up the same service across different hospitals.

Why do prices for this code differ between hospitals?

Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.

What this page is not

It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

81223

HCPCS

HC CF (CFTR) SEQUENCING

Verified from hospital fileNot a bill estimate

iDirect answer

Based on the latest published hospital price files, code 81223 (HC CF (CFTR) SEQUENCING) appears at 23 hospitals with disclosed cash prices from $239 to $5,121. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Published-price availability

hospitals publish a price

list this service without a published price

Cash

List

Negotiated

Allowed

A blank price (“—”) means a hospital names this service but did not publish a dollar amount — it is not a free service or a $0 price.

Compare 81223 prices

Filter by hospital, city, setting, or payer — the summary and charts update with your filters.

Based on hospital-published prices verified from each hospital’s own file. Coverage expands as data is verified.

Published cash prices for code 81223 vary by about 21× across the 19 hospitals with disclosed prices here — from $239 to $5,121. Shopping around can matter.

Hospitals

Prices shown

$239

Lowest cash

$5,121

Highest cash

code 81223 cash price25 disclosed · 19 hospitals

$239median ~$1,100$5,121

Lowest cash price by hospital

Cash price by city

Reflects your current filters.

Cash price by city$239 – $3,337

Stanford · 1 hospital$239–$3,337
Manitowoc · 1 hospital$835
Mequon · 1 hospital$873
New Berlin · 1 hospital$873
Oak Creek · 1 hospital$873
Milwaukee · 1 hospital$1,058

32 prices shown.

Service	Hospital	Code	List price	Cash price	Negotiated range	Allowed (median)
HC CF (CFTR) SEQUENCING Inpatient & outpatient	Endeavor Health Edward Hospital	81223 HCPCS	$5,121	$5,121	—	—
Cftr gene full sequence Outpatient	Endeavor Health Edward Hospital	81223 HCPCS	—	—	$499 – $845	—
Hc Cftr Gene Analysis; Full Gene Sequence Inpatient & outpatient	University of Chicago Medical Center	81223 HCPCS	—	—	—	—
Hc Cystic Fibrosis Diagnostic Testing Gene Analysis; Full Gene Sequence Inpatient & outpatient	University of Chicago Medical Center	81223 HCPCS	—	—	—	—
Cftr gene full sequence Outpatient	University of Chicago Medical Center	81223 HCPCS	—	—	—	—
CYSTIC FIBROSIS GENE Outpatient	Advocate Illinois Masonic Medical Center	81223 CPT	$2,120	$1,060	$499 – $2,268	—
CYSTIC FIBROSIS GENE Inpatient	Advocate Lutheran General Hospital	81223 CPT	$2,120	$1,060	$926 – $1,696	—
CYSTIC FIBROSIS GENE Outpatient	Advocate Condell Medical Center	81223 CPT	$2,120	$1,060	$499 – $2,268	—
CYSTIC FIBROSIS GENE Outpatient	Advocate Good Samaritan Hospital	81223 CPT	$2,120	$1,060	$499 – $2,268	—
CYSTIC FIBROSIS GENE Outpatient	Advocate South Suburban Hospital	81223 CPT	$2,120	$1,060	$499 – $2,268	—
HC CFTR, GENE ANALYSIS, FULL GENE SEQUENCE Outpatient	Froedtert Hospital	81223 CPT	$1,924	$1,058	$485 – $2,495	—
CYSTIC FIBROSIS GENE Inpatient	Aurora BayCare Medical Center	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Medical Center Burlington	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
CYSTIC FIBROSIS GENE Outpatient	Aurora Medical Center Burlington	81223 CPT	$2,200	$1,100	$399 – $1,870	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Medical Center Bay Area	81223 CPT	$2,200	$1,100	$1,320 – $1,861	—
CYSTIC FIBROSIS GENE Outpatient	Aurora Medical Center Bay Area	81223 CPT	$2,200	$1,100	$399 – $1,861	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Medical Center Fond du Lac	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
CYSTIC FIBROSIS GENE Outpatient	Aurora Medical Center Fond du Lac	81223 CPT	$2,200	$1,100	$399 – $1,870	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Medical Center Grafton	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Medical Center Kenosha	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
CYSTIC FIBROSIS GENE Inpatient	Aurora Lakeland Medical Center	81223 CPT	$2,200	$1,100	$1,320 – $1,870	—
HC CFTR, GENE ANALYSIS, FULL GENE SEQUENCE Inpatient	Froedtert Holy Family Memorial Hospital	81223 CPT	$1,519	$835	$911 – $1,337	—
HC CFTR, GENE ANALYSIS, FULL GENE SEQUENCE Inpatient	Froedtert Community Hospital - Mequon	81223 CPT	$1,588	$873	$953 – $1,397	—
HC CFTR, GENE ANALYSIS, FULL GENE SEQUENCE Outpatient	Froedtert Community Hospital - New Berlin	81223 CPT	$1,588	$873	$499 – $1,397	—
HC CFTR, GENE ANALYSIS, FULL GENE SEQUENCE Inpatient	Froedtert Community Hospital - Oak Creek	81223 CPT	$1,588	$873	$953 – $1,397	—

How to read these prices

Cash price: The discounted self-pay price for paying directly, without insurance.
List price: The hospital’s full undiscounted charge — rarely what anyone pays.
Negotiated rate: A rate for a specific insurer and plan; your share depends on your benefits.
Allowed amount: A historical reference for what was actually allowed, where disclosed.

Hospitals that publish 81223 prices

Open a hospital to see this code in the context of its full published prices.

Code 81223: frequently asked

What does code 81223 cost?: Across the published hospital price files, the disclosed cash price for 81223 ranges from $239 to $5,121. This is public hospital price transparency data, not a guaranteed estimate of your bill.
Will this be my final bill?: Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.
What is code 81223?: 81223 is the billing code hospitals use to identify "HC CF (CFTR) SEQUENCING" on their published price files. We use it to line up the same service across different hospitals.
Why do prices for this code differ between hospitals?: Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.
What this page is not: It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

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